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葫蘆素B
分析標(biāo)準(zhǔn)品,HPLC≥97%
Cucurbitacin B
CAS號：6199-67-3
分子式：C32H46O8
分子量：558.71
MDL：MFCD07778083
貨號 | 規(guī)格/參數(shù)/品牌 | 價格 | 貨期 |
YJ-B20523-5mg | 分析標(biāo)準(zhǔn)品,HPLC≥97% | ￥460.00 | 現(xiàn)貨 |
YJ-B20523-20mg | 分析標(biāo)準(zhǔn)品,HPLC≥97% | ￥900.00 | 現(xiàn)貨 |
A10155-20mg | 分析標(biāo)準(zhǔn)品,含量86.8%，可溯源 | ￥1700.00 | 現(xiàn)貨 |
JV30067-5mg | ≥98% | ￥469.00 | 現(xiàn)貨 |
JV30067-25mg | ≥98% | ￥1149.00 | 現(xiàn)貨 |
JV30067-100mg | ≥98% | ￥3299.00 | 現(xiàn)貨 |
產(chǎn)品介紹
熔點：184-186℃
沸點：699.3℃ at 760 mmHg
比旋光度：D25 +88° (c = 1.55 in ethanol)
外觀：白色晶體
溶解性：易溶于氯仿
儲存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(25篇)
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21. [IF=3.391] Jiaxin Xu et al."Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity."Arch Biochem Biophys. 2020 May;684:108314
20. [IF=1.98] Yanting Chai et al."Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells."Med Sci Monitor. 2018; 24: 9251–9258
19. [IF=2.439] Wenjing Ma et al."Cucurbitacin B induces inhibitory effects via the CIP2A/PP2A/C-KIT signaling axis in t(8;21) acute myeloid leukemia."J Pharmacol Sci. 2019 Apr;139:304
18. [IF=3.205] Zhibin Wang et al."Simultaneous determination of cucurbitacin B and cucurbitacin E in rat plasma by UHPLC-MS/MS: A pharmacokinetics study after oral administration of cucurbitacin tablets."J Chromatogr B. 2017 Oct;1065-1066:63
17. [IF=3.267] Pengfei Liu et al."Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung Cancer."Molecules. 2019 Jan;24(3):647
16. [IF=3.417] Fen Cai et al."Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/adriamycin cells."Oncol Rep. 2016 Aug;36(2):1180-1186
15. [IF=4.784] Shanshan Qin et al."Cucurbitacin B induces inhibitory effects via CIP2A/PP2A/Akt pathway in glioblastoma multiforme."Mol Carcinogen. 2018 Jun;57(6):687-699
14. Liu, Xuewen, et al. "Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells." Oncology reports 38.1 (2017): 271-278.https:##doi.org/10.3892/or.2017.5648
13. Qin, Shanshan, et al. "Cucurbitacin B induces inhibitory effects via CIP2A/PP2A/Akt pathway in glioblastoma multiforme." Molecular carcinogenesis 57.6 (2018): 687-699.
12. Ma, Wenjing, et al. "Cucurbitacin B induces inhibitory effects via the CIP2A/PP2A/C-KIT signaling axis in t (8; 21) acute myeloid leukemia." Journal of pharmacological sciences 139.4 (2019): 304-310.https:##doi.org/10.1016/j.jphs.2018.12.010
11. Liu, Pengfei, et al. "Cucurbitacin B induces the lysosomal degradation of EGFR and suppresses the CIP2A/PP2A/Akt signaling Axis in Gefitinib-resistant non-small cell lung Cancer." Molecules 24.3 (2019): 647.647; https:##doi.org/10.3390/molecules24030647
10. Xu, Jiaxin, et al. "Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity." Archives of biochemistry and biophysics 684 (2020): 108314.https:##doi.org/10.1016/j.abb.2020.108314
9. Chai, Yanting, et al. "Cucurbitacin B inhibits the Hippo-YAP signaling pathway and exerts anticancer activity in colorectal cancer cells." Medical science monitor: international medical journal of experimental and clinical research 24 (2018): 9251.10.12659
8. Cai, Fen, et al. "Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/adriamycin cells." Oncology reports 36.2 (2016): 1180-1186.https:##doi.org/10.3892/or.2016.4892
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