業(yè)執(zhí)照.jpg)
漢黃芩素
分析標(biāo)準(zhǔn)品,HPLC≥98%
Wogonin
CAS號(hào)：632-85-9
分子式：C16H12O5
分子量：284.27
MDL：MFCD00017736
貨號(hào) | 規(guī)格/參數(shù)/品牌 | 價(jià)格 | 貨期 |
YJ-B20489-20mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥470.00 | 現(xiàn)貨 |
YJ-B20489-100mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥1100.00 | 現(xiàn)貨 |
YJ-B20489-500mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥2980.00 | 現(xiàn)貨 |
JT90133-1ml買5贈(zèng)1 | 10mM in DMSO | ￥563.00 | 現(xiàn)貨 |
產(chǎn)品介紹
熔點(diǎn)：203-206℃
沸點(diǎn)：518.8 ℃ at 760 mmHg
外觀：黃色針狀結(jié)晶
溶解性：DMSO中的溶解度:50mg/ml（需超聲）
儲(chǔ)存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(xiàn)(84篇)
84. [IF=2.5] Weixian Shao et al."Study on the Specifications of Scutellariae Radix in Da-Chai-Hu-Tang Based on Efficacy in a Rat Model of Large Intestine Damp-Heat Syndrome and Chemical Composition Differences."CHEMISTRY & BIODIVERSITY.2025 Jul;:e01198
83. [IF=5.4] Ni Xu et al."Modulation of Glycolytic Metabolic Reprogramming and the TLR4/NF-κB/NLRP3 Pathway: Comparative Analysis of Anti-inflammatory Activity Between Two Dosage Forms of Pudilan Xiaoyan."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jun;:120204
82. [IF=14.1] Chuanrui Ma et al."Wogonin Attenuates Atherosclerosis via KLF11-Mediated Suppression of PPARα-YAP1-Driven Glycolysis and Enhancement of ABCA1/G1-Mediated Cholesterol Efflux."Advanced Science.2025 May;:2500610
81. [IF=2.7] Dan-ni Chen et al."Promotion of a quality standard for Scutellariae radix based on the anti-inflammatory efficacy-oriented quality marker of the effect-constituent index."Analytical Methods.2024 Nov;:
80. [IF=3.8] Song Yang et al."Wogonin suppresses proliferation, invasion and migration in gastric cancer cells via targeting the JAK-STAT3 pathway."Scientific Reports.2024 Dec;14(1):1-15
79. [IF=4.8] Xian-Heng Zhang et al."Chinese herbal medicines and its active ingredient wogonin can improve immune inflammation in psoriatic arthritis."INTERNATIONAL IMMUNOPHARMACOLOGY.2025 Feb;147:113984
78. [IF=3.1] Yang Hui et al."Wogonin attenuates inflammation and oxidative stress in acute lung injury via regulating PPARα, AKT, and NRF2."NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY.2025 Feb;:1-12
77. [IF=1.2] Meili Yang et al."Exploring the potential mechanism of Andrographis paniculata compounds against neurodegenerative diseases based on network pharmacology and molecular docking."CHINESE JOURNAL OF ANALYTICAL CHEMISTRY.2025 Feb;:100514
76. [IF=6.7] Jingyan Zhang et al."Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis."PHYTOMEDICINE.2025 Mar;:156708
75. [IF=5.6] Hao Guo et al."Research on the synergistic optimization of Scutellaria baicalensis yield, quality and soil environment by key microorganisms, driven by the combined approach of reducing chemical fertilizer usage while incorporating organic fertilizer."IND
74. [IF=5.1] Jing-Qun Liu et al."Apigenin ameliorates lupus nephritis by inhibiting SAT3 signaling in CD8+T cells."Food & Function.2024 Sep;:
73. [IF=4.2] Xinyue Wang et al."Mechanistic investigation of wogonin in delaying the progression of endothelial mesenchymal transition by targeting the TGF-β1 pathway in pulmonary hypertension."EUROPEAN JOURNAL OF PHARMACOLOGY.2024 Sep;978:176786
72. [IF=4.3] Hujun Du et al."Exploring the Underlying Mechanisms of Qingxing Granules Treating H1N1 Influenza Based on Network Pharmacology and Experimental Validation."Pharmaceuticals.2024 Jun;17(6):731
71. [IF=5.7] Yujing Liu et al."Wogonin Inhibits Colorectal Cancer Proliferation and Epithelial Mesenchymal Transformation by Suppressing Phosphorylation in the AKT Pathway."AMERICAN JOURNAL OF CHINESE MEDICINE.10.1142/S0192415X24500460
70. [IF=7.9] Yanqin Luo et al."Scutellaria baicalensis water decoction ameliorates lower respiratory tract infection by modulating respiratory microbiota."PHYTOMEDICINE".2024 May;:155706
69. [IF=1.6] Zhang Jie et al."Exploration of the effect and mechanism of Scutellaria barbata D. Don in the treatment of ovarian cancer based on network pharmacology and in vitro experimental verification."MEDICINE.2023 Dec;102(51):e36656
68. [IF=1.8] Yue Qian et al."Si Miao San relieves hyperuricemia by regulating intestinal flora."BIOMEDICAL CHROMATOGRAPHY.2023 Dec;:e5807
67. [IF=5.4] Botong Li et al."Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways."JOURNAL OF ETHNOPHARMACOLOGY.2024 Mar;322:117578
66. [IF=5.4] Liangxin Zhao et al."UPLC-Q-Exactive/MS based analysis explore the correlation between components variations and anti-influenza virus effect of four quantified extracts of Chaihu Guizhi decoction."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;:117318
65. [IF=1.8] Ying Yang et al."Anti-osteoporosis bioactivity evaluation in zebrafish model of raw and salt-processed Achyranthes bidentata followed by liquid chromatography–mass spectrometry analysis and correlation analysis."BIOMEDICAL CHROMATOGRAPHY.10.1002/bmc.5742
64. [IF=7] Caijun Ren et al."Antioxidant Polyphenols from Lespedeza bicolor Turcz. Honey: Anti-Inflammatory Effects on Lipopolysaccharide-Treated RAW 264.7 Macrophages."Antioxidants.10.3390/antiox12101809
63. [IF=4.3] Bao-Fei Yan et al."Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway."WORLD JOURNAL OF GASTROENTEROLOGY.2023 Aug 21; 29(31): 4744–4762
62. [IF=5.2] Guo Huanyu et al."The combined effect of a novel formula of herbal extracts on bacterial infection and immune response in Micropterus salmoides."Frontiers in Microbiology.2023 Jun;14:
61. [IF=5.4] Miaomiao Liu et al."Qingjin Huatan decoction protects mice against influenza a virus pneumonia via the chemokine signaling pathways."JOURNAL OF ETHNOPHARMACOLOGY.2023 Dec;317:116745
60. [IF=1.555] Huang Zhen et al."Screening Antibacterial Constituents of Scutellaria Radix Based on Spectrum–Effect Relationships Between HPLC Fingerprints and the Inhibition of Oral Bacteria."JOURNAL OF CHROMATOGRAPHIC SCIENCE.2023 Mar;:
59. [IF=3.246] Yue Qian et al."A Network Pharmacology Method Combined with Molecular Docking Verification to Explore the Therapeutic Mechanisms Underlying Simiao Pill Herbal Medicine against Hyperuricemia."Biomed Research International.2023;2023:2507683
58. [IF=2.586] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Shuang-Huang-Lian powder injection using ultra-high-performance liquid chromatography-quadrupole time-of-flight-mass spectrometry and ultra-high-performance liquid c
57. [IF=4.831] Jing Sun et al."Fourier transform infrared spectroscopic markers of the scorching degree of Scutellariae Radix related to the variation patterns of flavonoids and carbohydrates."SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY.2023 Apr;2
56. [IF=7.169] Dong Ya-ping et al."Skullcapflavone II, a novel NQO1 inhibitor, alleviates aristolochic acid I-induced liver and kidney injury in mice."ACTA PHARMACOLOGICA SINICA.2023 Jan;:1-13
55. [IF=3.318] Hui Luo et al."Efficacy identification and active compounds screening of topically administration of Scutellaria Radix in oral ulcer."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Dec;:123571
54. [IF=5.195] Bao-Fei Yan et al."Huangqin decoction mitigates hepatic inflammation in high-fat diet-challenged rats by inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Mar;303:115999
53. [IF=7.291] Liu Xiaojuan et al."Genome-wide analysis of cytochrome P450 genes in Citrus clementina and characterization of a CYP gene encoding flavonoid 3'-hydroxylase."Horticulture Research.2022 Dec;:
52. [IF=5.195] Xiaojing Wang et al."Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;:115919
51. [IF=5.195] Weicong Chen et al."Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts."JOURNAL OF ETHNOPHARMACOLOGY.2022 Oct;:115825
50. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199
49. [IF=5.195] Zhen Huang et al."Efficacy confirmation of Scutellaria baicalensis Georgi in the treatment of periodontitis via topical administration and active ingredients screening."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jan;300:115699
48. [IF=5.195] Xin Deng et al."A novel strategy for active compound efficacy status identification in multi-tropism Chinese herbal medicine (Scutellaria baicalensis Georgi) based on multi-indexes spectrum-effect gray correlation analysis."JOURNAL OF ETHNOPHARMACOLOGY.20
47. [IF=5.895] Junxiu Wang et al."Betulin, Synthesized by PpCYP716A1, Is a Key Endogenous Defensive Metabolite of Peach against Aphids."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2022;70(40):12865–12877
46. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747
45. [IF=6.212] Fei Huang et al."Discovery of conversion driven by β-glucuronidase from flavone glycoside to aglycone and application in identifying the raw Scutellariae Radix."Arabian Journal of Chemistry.2022 Aug;:104216
44. [IF=3.614] Huanyu Guan et al."Deciphering the chemical constituents of Shengjiang Xiexin decoction by ultra-high-performance liquid chromatography-quadrupole/orbitrap high-resolution mass spectrometry and the impact of 20 characteristic components on multidrug resis
43. [IF=5.195] Mengmeng Song et al."Homeostatic regulation of the aryl hydrocarbon receptor-cytochrome P450 1a axis by Scutellaria baicalensis-Coptis chinensis herb pair and its main constituents."JOURNAL OF ETHNOPHARMACOLOGY.2022 Jul;:115545
42. [IF=8.025] Ying Wang et al."Inhibitory activities of flavonoids from Scutellaria baicalensis Georgi on amyloid aggregation related to type 2 diabetes and the possible structural requirements for polyphenol in inhibiting the nucleation phase of hIAPP aggregation."INT
41. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155
40. [IF=3.935] Yizhu Wang et al."Effects of Scutellaria baicalensis Georgi. on Intestinal Flora in Rats with Spleen Deficiency and Damp-heat."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2022 May;:114831
39. [IF=5.268] Bingyan Yang et al."Improved stability and pharmacokinetics of wogonin through loading into PASylated ferritin."COLLOIDS AND SURFACES B-BIOINTERFACES. 2022 Aug;216:112515
38. [IF=5.923] Shiwei Wang et al.Inhibition of Virulence Factors and Biofilm Formation by Wogonin Attenuates Pathogenicity of Pseudomonas aeruginosa PAO1 via Targeting pqs Quorum-Sensing System.Int J Mol Sci. 2021 Jan;22(23):12699
37. [IF=2.447] Fang-Mei Zhou et al."Protective effects of flavonoids from the leaves of Carya cathayensis Sarg. against H2O2?induced oxidative damage and apoptosis in vitro."Exp Ther Med. 2021 Dec;22(6):1-11
36. [IF=2.629] Wang Hui-Nan et al."Comparison of Pharmacokinetics and Tissue Distribution Characteristics of Three Diterpenoid Esters in Crude and Prepared Semen Euphorbiae."Evid-Based Compl Alt. 2021;2021:7402120
35. [IF=2.877] Wanli Ji et al."Identifying the active compounds and mechanism of action of Banxia Xiexin decoction for treating ethanol-induced chronic gastritis using network pharmacology combined with UPLC–LTQ–Orbitrap MS."Comput Biol Chem. 2021 Aug;93:107535
34. [IF=3.361] Mengmeng Yuan et al."The interaction of dietary flavonoids with xanthine oxidase in vitro: molecular property-binding affinity relationship aspects."Rsc Adv. 2019 Apr;9(19):10781-10788
33. [IF=3.935] Chenglong Sun et al."A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi."J Pharmaceut Biomed. 2020 Feb;179:113014
32. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625
31. [IF=4.759] Yueping Jiang et al."Application of multifold characteristic ion filtering combined with statistical analysis for comprehensive profiling of chemical constituents in anti-renal interstitial fibrosis I decoction by ultra-high performance liquid chromatogra
30. [IF=5.11] Xiaonan Liu et al."De Novo Biosynthesis of Multiple Pinocembrin Derivatives in Saccharomyces cerevisiae."Acs Synth Biol. 2020;9(11):3042–3051
29. [IF=5.279] Wenqin Li et al."Discovery of Natural Products as Multitarget Inhibitors of Insect Chitinolytic Enzymes through High-Throughput Screening."J Agr Food Chem. 2021;69(37):10830–10837
28. [IF=5.81] Cui Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369
27. [IF=3.205] Zhuangzhuang Li et al."Simultaneous quantification of fifteen compounds in rat plasma by LC-MS/MS and its application to a pharmacokinetic study of Chaihu-Guizhi decoction."J Chromatogr B. 2019 Jan;1105:15
26. [IF=3.361] Huanyu Guan et al."Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out
25. [IF=3.935] Yanqiu Gu et al."Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix."J Pharmaceut Biomed. 2019 Feb;164:550
24. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239
23. Xu, Jun. "Improved approaches and strategies for analyzing decoctions of medicinal herbs." (2016).
22. Yanqiu, et al. "Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix. " Journal of pharmaceutical and biomedical analysis 164
21. Sun, Chenglong, et al. "A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi." Journal of pharmaceutical and biomedical analysis 179 (2020): 113014.https:##doi.org/10.1016/j.jpba.2019.11
20. Cheng, Yan, et al. "Controlled Extraction of Flavonoids From Radix Scutellariae by Subcritical Water." CLEAN–Soil, Air, Water 44.3 (2016): 299-303.https:##doi.org/10.1002/clen.201300193
19. 莉莉,陳勇,張蒙偉,鄢紅霞,高守紅,陳萬(wàn)生.UHPLC-MS/MS法測(cè)定新冠肺炎經(jīng)驗(yàn)方寒濕郁肺湯中11種主成分的含量[J].藥學(xué)實(shí)踐雜志,2021,39(02):148-151+156.
18. 張慧, 李思雨, 馮宏玲,等. 基于效應(yīng)成分指數(shù)的雙黃連制劑質(zhì)量控制研究[J]. 藥學(xué)學(xué)報(bào), 2019, 054(012):2149-2154.
17. 任永申, 鄧鑫, 雷蕾,等. 基于抑菌效應(yīng)成分指紋譜的黃芩質(zhì)量評(píng)價(jià)研究[J]. 藥學(xué)學(xué)報(bào), 2019, 054(012):2155-2161.
16. 袁杰, 李錟, 周利,等. 基于超高效液相色譜法和色差儀法的黃芩藥材質(zhì)量評(píng)價(jià)[J]. 世界中醫(yī)藥, 2019.
15. 李云靜, 張建逵, 趙玥,等. 黃芩藥材顏色及其有效成分的相關(guān)性[J]. 中國(guó)醫(yī)藥工業(yè)雜志, 2017(7).
14. 商利娜, 王亞靜, 趙鑫,等. 基于譜-效關(guān)系探究黃芩抑制白色念珠菌的質(zhì)量標(biāo)志物[J]. 中成藥, 2020, 042(005):1357-1361.
13. 柴沖沖,曹妍,毛民,王靖越,劉娜,李欣欣,張凱,陳東玲,魏龍吟,尹怡慧,李飛.基于電子舌技術(shù)評(píng)價(jià)黃芩酒炙前后滋味變化及其在黃芩飲片鑒別中的應(yīng)用研究[J].中國(guó)中藥雜志,2020,45(11):2552-2559.
12. 柴沖沖 毛民 袁金鳳 等. 不同方法軟化切制后的黃芩飲片顏色與5種黃酮類成分含量的相關(guān)性研究[J]. 中國(guó)中藥雜志 2019.
11. 王子凌云 梁琨 李國(guó)文. HPLC法測(cè)定芩杏清熱止咳顆粒中8種成分[J]. 中成藥 2019 041(005):995-999.
10. 程燕, 曲紹風(fēng), 李福偉,等. 黃芩中4種黃酮類化合物的亞臨界水提取研究[J]. 山東科學(xué), 2013(03):11-14.
9. 劉媛媛, 劉陶, 吳玉梅,等. 基于雌激素受體調(diào)節(jié)Nrf2-ARE通路的黃芩中抗氧化成分的篩選[J]. 中國(guó)藥理學(xué)通報(bào), 2019, 035(006):822-827.
8. 李淑嬌, 王宇卿. 基于HPLC-Q-TOF/MS法的黃芩血清藥物化學(xué)分析[J]. 中成藥, 2019, 41(03):117-122.
7. 王東超 魏穎 高佳琪 孫文 秦靈靈 蘭衛(wèi) 石浩霞 李博 徐暾海 劉銅華.HPLC同時(shí)測(cè)定糖痹康顆粒中黃芩苷、漢黃芩苷、黃芩素、漢黃芩素的含量[J].吉林中醫(yī)藥 2017 37(05):513-517.
6. 張婕,梁程程,楊愛(ài)仲,齊聰.增免抑瘤方及有效組分對(duì)卵巢癌干細(xì)胞裸鼠移植瘤Notch/Jagged1信號(hào)通路的影響[J].中國(guó)實(shí)驗(yàn)方劑學(xué)雜志,2020,26(15):46-53.
5. 李云靜 張建逵 王冰 等. 不同產(chǎn)地黃芩藥材中黃芩苷等5種黃酮類成分含量的比較[J]. 時(shí)珍國(guó)醫(yī)國(guó)藥 2016 027(012):2985-2988.
4. 許琳, 王營(yíng), 陳復(fù)興,等. 漢黃芩素對(duì)人NK細(xì)胞殺傷胃癌MKN45細(xì)胞的影響及其機(jī)制研究[J]. 免疫學(xué)雜志, 2014, 030(009):804-808.
3. 劉佳卓 王若琪 柳文媛. 反相高效液相色譜法測(cè)定千層紙素的含量和有關(guān)物質(zhì)[J]. 中南藥學(xué) 2019 017(001):93-98.
2. 段飛鵬 王英姿 李韶菁 等. 千金子甾醇在Caco-2細(xì)胞單層模型中的吸收研究[J]. 中草藥 2014 45(021):3136-3140.
1. 何悅 王四旺 肖會(huì)敏. HPLC法同時(shí)測(cè)定復(fù)方金銀花顆粒中10種成分的含量[J]. 藥學(xué)實(shí)踐雜志 2019 037(002):177-182.
從2011年開(kāi)始我們致力于在生命科學(xué)領(lǐng)域、生物醫(yī)學(xué)實(shí)驗(yàn)技術(shù)及論文潤(rùn)色服務(wù)，協(xié)助客戶各類實(shí)驗(yàn)服務(wù)及論文潤(rùn)色十余年，是客戶您值得信賴的科研合作伙伴!
如果您受時(shí)間、試驗(yàn)條件等限制而無(wú)法完成您的課題研究，歡迎您與我們聯(lián)系。
實(shí)驗(yàn)技術(shù)服務(wù)：
