執(zhí)照.jpg)
丹皮酚
分析標準品,HPLC≥98%
Paeonol
CAS號：552-41-0
分子式：C9H10O3
分子量：166.17
MDL：MFCD00008730
別名：2′-羥基-4′-甲氧基苯乙酮；芍藥醇；牡丹酚
貨號 | 規(guī)格/參數(shù)/品牌 | 價格 | 貨期 |
YJ-B20266-20mg | 分析標準品,HPLC≥98% | ￥200.00 | 現(xiàn)貨 |
JS24511-5g | 98% | ￥140.00 | 現(xiàn)貨 |
JS24511-25g | 98% | ￥270.00 | 現(xiàn)貨 |
JS24511-100g | 98% | ￥650.00 | 現(xiàn)貨 |
JS24511-500g | 98% | ￥1950.00 | 現(xiàn)貨 |
A10102-50mg | 分析標準品,含量99.5%，可溯源 | ￥350.00 | 現(xiàn)貨 |
產(chǎn)品介紹
Paeonol 是一種從牡丹中提取的活性物質(zhì)，可抑制 MAO-A 和 MAO-B，IC50 分別為 54.6 μM 和 42.5 μM。
熔點：48-50℃(lit.)
沸點：154 ℃ / 20mmHg
外觀：白色或微黃色有光澤的針狀結(jié)晶，無色針狀結(jié)晶（乙醇）。
溶解性：Ethanol : 50 mg/mL (300.90 mM; Need ultrasonic)
DMSO : ≥ 38 mg/mL (228.68 mM)
H2O : 1 mg/mL (6.02 mM; Need ultrasonic)
儲存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(58篇)
58. [IF=5.6] Jing Yang et al."Isolation, purification and comparison of soluble active substances from four peony roots."INDUSTRIAL CROPS AND PRODUCTS.2024 Dec;222:119886
57. [IF=3.3] Xue Chen et al."Role of IGF1/IGFR signaling pathway in neuroprotective effect of Shengmai Dihuang Decoction on CIH-induced cognitive impairment."Journal of Traditional and Complementary Medicine.2024 Nov;:
56. [IF=7.2] Lili Zhou et al."Aptamer-conjugated dual-loaded liposomes exhibit synergistic effects in hepatic tumor treatment."Applied Materials Today.2025 Apr;43:102659
55. [IF=3.1] Xuanxuan Zhou et al."Exploration of material basis: Chemical composition profile and metabolic profile in Xiao Jianzhong Granules."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2025 Aug;260:116793
54. [IF=4.8] Ke-han Chen et al."Evaluating the efficacy and safety of emodin, luteolin, and paeonol combination from Dahuang Mudan decoction in ameliorating ulcerative colitis."JOURNAL OF ETHNOPHARMACOLOGY.2025 Apr;346:119692
53. [IF=4.8] Yao Zhang et al."Paeonol and glycyrrhizic acid in combination ameliorate the recurrent nitroglycerin-induced migraine-like phenotype in rats by regulating the GABBR2/TRPM8/PRKACA/TRPV1 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jun;:118464
52. [IF=3.8] Deng Bo et al."Paeonol attenuated high glucose-induced apoptosis via up-regulating miR-223-3p in mouse cardiac microvascular endothelial cells."Scientific Reports.2024 Jul;14(1):1-8
51. [IF=6.5] Ziwei Wang et al."Combined metabolomics and bioactivity assays kernelby-productsof two native Chinese cherry species: The sources of bioactive nutraceutical compounds."Food Chemistry-X.2024 Oct;23:101625
50. [IF=2.5] Jing Liu et al."Phytochemical Identification and Anti-Oxidative Stress Effects Study of Cimicifugae Rhizoma Extract and Its Major Component Isoferulic Acid."Separations.2024 Jun;11(6):175
49. [IF=5.4] Guiming Yan et al."Paeonol attenuates nonalcoholic steatohepatitis by regulating intestinal flora and AhR/NLRP3/Caspase-1 metabolic pathway."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118147
48. [IF=3.4] Yuerong Qian et al."Development of a novel human stratum corneum mimetic phospholipid -vesicle-based permeation assay models for in vitro permeation studies."DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY.10.1080/03639045.2024.2331242
47. [IF=3.4] Yanhua Jiang et al."Network pharmacology combined with lipidomics to reveal the regulatory effects and mechanisms of Kangzao granules in the hypothalamus of rats with central precocious puberty."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS".2024 May;
46. [IF=7.9] Meng Zhao et al."Paeonol alleviates ulcerative colitis in mice by increasing short-chain fatty acids derived from Clostridium butyricum."PHYTOMEDICINE.10.1016/j.phymed.2023.155056
45. [IF=1.8] Yue Qian et al."Si Miao San relieves hyperuricemia by regulating intestinal flora."BIOMEDICAL CHROMATOGRAPHY.2023 Dec;:e5807
44. [IF=5.4] Mingxiang Xie et al."Molecular mechanism of PSORI-CM01 for psoriasis by regulating the inflammatory cytokines network."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;318:116935
43. [IF=8.1] Ziwei Wang et al."Comparative antioxidant activity and untargeted metabolomic analyses of cherry extracts of two Chinese cherry species based on UPLC-QTOF/MS and machine learning algorithms."FOOD RESEARCH INTERNATIONAL.2023 Sep;171:113059
42. [IF=2.464] Hao Mingxuan et al."Paeonol Inhibits Glioma Growth In Vivo and In Vitro by Inducing Apoptosis and Cell Cycle Arrest."Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy.2023 Mar;:1-9
41. [IF=3.246] Yue Qian et al."A Network Pharmacology Method Combined with Molecular Docking Verification to Explore the Therapeutic Mechanisms Underlying Simiao Pill Herbal Medicine against Hyperuricemia."Biomed Research International.2023;2023:2507683
40. [IF=6.449] Xiaoxiao Wang et al."Physicochemical analysis, sensorial evaluation, astringent component identification and aroma-active compounds of herbaceous Peony (Paeonia lactiflora Pall) black tea."INDUSTRIAL CROPS AND PRODUCTS.2023 Mar;193:116159
39. [IF=3.385] Yaxue Li et al."The effect of dietary paeonol on growth performance, antioxidant enzyme activities and gene expressions of Genetic Improvement of Farmed Tilapia juveniles (Oreochromis niloticus)."Aquaculture Reports.2022 Oct;26:101302
38. [IF=4.996] Yuan Jie et al."Systematic characterization of the components and molecular mechanisms of Jinshui Huanxian granules using UPLC-Orbitrap Fusion MS integrated with network pharmacology."Scientific Reports.2022 Jul;12(1):1-24
37. [IF=5.135] Lijuan Yu et al."Acetylferulic paeonol ester: A new feed additive reduces lipid accumulation in the liver of Nile tilapia (Oreochromis niloticus) by modulating lipid and glucose metabolism."AQUACULTURE.2022 Dec;561:738671
36. [IF=2.952] Shouzhu Xu et al."Paeonol alleviates lipopolysaccharide?induced hepatocytes injury through alteration of mitochondrial function and NF?κB translocation."Mol Med Rep. 2021 Nov;24(5):1-9
35. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950
34. [IF=3.512] Yahong Chen et al."Identification of Potential Human Ryanodine Receptor 1 Agonists and Molecular Mechanisms of Natural Small-Molecule Phenols as Anxiolytics."Acs Omega. 2021;XXXX(XXX):XXX-XXX
33. [IF=3.69] Qianni Duan et al."Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2."J Ethnopharmacol. 2020 Mar;249:112405
32. [IF=3.935] Zhengchao Ji et al."Global identification and quantitative analysis of representative components of Xin-Nao-Kang Capsule, a traditional Chinese medicinal formula, by UHPLC-Q-TOF-MS and UHPLC-TQ-MS."J Pharmaceut Biomed. 2021 May;198:114002
31. [IF=3.996] Liu Dong-Hai et al."Anticonvulsant and Neuroprotective Effects of Paeonol in Epileptic Rats."Neurochem Res. 2019 Nov;44(11):2556-2565
30. [IF=3.998] Mei Liyan et al."Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p."Sci Rep-Uk. 2019 Dec;9(1):1-15
29. [IF=4.36] Xiaoli Zhao et al."Transcriptomic study of the mechanism by which the Kai Yu Zhong Yu recipe improves oocyte quality in a stressed mouse model."J Ethnopharmacol. 2021 Oct;278:114298
28. [IF=4.53] Du Jikun et al."Paeonol triggers apoptosis in HeLa cervical cancer cells: the role of mitochondria-related caspase pathway."Psychopharmacology. 2021 Mar 12
27. [IF=5.875] Fangyuan Wang et al."Paeonol-loaded PLGA nanoparticles as an oral drug delivery system: Design, optimization and evaluation."Int J Pharmaceut. 2021 Jun;602:120617
26. [IF=6.165] Jinpeng Liu et al."Temperature-sensitive lyotropic liquid crystals as systems for transdermal drug delivery."J Mol Liq. 2021 Mar;326:115310
25. [IF=7.514] Lijuan Yu et al."Synthesis and evaluation of acetylferulic paeonol ester and ferulic paeonol ester as potential antioxidants to inhibit fish oil oxidation."Food Chem. 2021 Dec;365:130384
24. [IF=3.361] Xia Liu et al."Paeonol attenuates acute lung injury by inhibiting HMGB1 in lipopolysaccharide-induced shock rats."Int Immunopharmacol. 2018 Aug;61:169
23. [IF=5.076] Huichao Xie et al."An Available Strategy for Nasal Brain Transport of Nanocomposite Based on PAMAM Dendrimers via In Situ Gel."Nanomaterials-Basel. 2019 Feb;9(2):147
22. [IF=6.529] Xing-Yan Liu et al."The activity of Hou-Po-Da-Huang-Tang is improved through intestinal bacterial metabolism and Hou-Po-Da-Huang-Tang selectively stimulate the growth of intestinal bacteria associated with health."Biomed Pharmacother. 2017 Oct;94:794
21. Duan, Qianni, et al. "Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2." Journal of ethnopharmacology 249 (2020): 112405.https:##doi.org/10.1016/j.jep.2019.112405
20. Xie H, Li L, Sun Y, Wang Y, Gao S, Tian Y, Ma X, Guo C, Bo F, Zhang L. An Available Strategy for Nasal Brain Transport of Nanocomposite Based on PAMAM Dendrimers via In Situ Gel. Nanomaterials. 2019; 9(2):147. https:##doi.org/10.3390/nano9020147
19. Liu, Dong-Hai, et al. "Anticonvulsant and neuroprotective effects of paeonol in epileptic rats." Neurochemical research 44.11 (2019): 2556-2565.
18. 段昆,高霞,耿婷,陳夏霖,曹亮,肖偉,王振中.基于血清代謝組學(xué)技術(shù)探討桂枝茯苓膠囊及其主要成分治療原發(fā)性痛經(jīng)的作用機制[J].中國新藥雜志,2020,29(18):2066-2074.
17. 趙秋龍,卞曉坤,錢大瑋,宿樹蘭,郭盛,王團結(jié),段金廒.桂枝茯苓膠囊在原發(fā)性痛經(jīng)模型大鼠血漿、膽汁、尿液和糞便中的代謝產(chǎn)物研究[J].藥物分析雜志,2021,41(01):51-63.
16. 代天,楊萍,劉波,張?zhí)K川.芍藥醇調(diào)控miR-122-5p/GSTM1分子軸對缺血再灌注心肌細胞存活的影響[J].中國藥師,2021,24(02):232-236.
15. 代天,楊萍,劉波,張?zhí)K川.芍藥醇調(diào)控miR-122-5p/GSTM1分子軸對缺血再灌注心肌細胞存活的影響[J].中國藥師,2021,24(02):232-236.
14. 牛琴,鈕紅麗,翟俊英,王韻一,馬志賓,王莉.丹皮酚通過內(nèi)質(zhì)網(wǎng)應(yīng)激和線粒體損傷途徑促進卵巢癌細胞凋亡[J].廣州中醫(yī)藥大學(xué)學(xué)報,2020,37(10):1991-1998.
13. 程江雪, 唐志書, 郭東艷, et al. 不同配伍配比對赤芍-當(dāng)歸藥對中10個成分溶出量的影響研究[J]. 藥物分析雜志, 2019, v.39(09):73-80.
12. 付士朋, 沈宏偉, 王謙博,等. 赤芍飲片加工工藝的優(yōu)化[J]. 中成藥, 2019(8).
11. 王化, 何丹嬈, 朱良玉,等. HPLC法同時測定赤芍中9個活性成分的含量[J]. 中草藥, 2018, 049(003):708-711.
10. 王秀秀, 李智慧, 石森林,等. 桂枝茯苓濃縮丸多指標成分體外溶出度研究[J]. 中華中醫(yī)藥學(xué)刊, 2014, 032(012):2875-2877.
9. 吳素香, 石森林, 葛衛(wèi)紅,等. 桂枝茯苓丸有效成分與物質(zhì)組的溶出相關(guān)性[J]. 中成藥, 2016, 38(11):2360-2365.
8. 劉靈改, 支旭然, 吳宗耀,等. 高效液相色譜法測定防芷鼻咽顆粒中7種活性成分的含量[J]. 中國藥學(xué)雜志, 2014, 49(017):1554-1558.
7. 劉靈改 支旭然 郭進 等. HPLC-MS法同時測定防芷鼻咽顆粒中6個成分的含量[J]. 藥物分析雜志 2014(5):830-835.
6. 段昆, 高霞, 耿婷, et al. 桂枝茯苓膠囊及其主要成分對原發(fā)性痛經(jīng)模型大鼠腸道菌群的影響[J]. 中國藥房, 2020, v.31;No.677(11):45-51.
5. 張佳歡 李智慧 石森林 等. 不同劑型桂枝茯苓丸的溶出度比較[J]. 浙江中醫(yī)雜志 2019 v.54;No.582(09):73-74.
4. 趙婷秀 曹迪 茆文莉 等. HPLC-QTOF-MS分析六味地黃丸不同部位的化學(xué)成分[J]. 中藥新藥與臨床藥理 2018 029(004):489-496.
3. 孫晶, 魏永利, 李克明,等. 高效液相色譜法測定6個不同產(chǎn)地的牡丹葉中丹皮酚和芍藥苷含量[J]. 山東科學(xué), 2020, 000(001):24-28.
2. 向極釬, 楊永康, 龍瀾,等. 湖北建始丹皮HPLC指紋圖譜研究[J]. 湖北農(nóng)業(yè)科學(xué), 2013(22):5521-5524.
1. 張喬 俞洋洋 王勤輝 等. 六味地黃制劑多類型成分快速分析和"一測多評"方法建立[J]. 中國實驗方劑學(xué)雜志 2014 020(006):81-86.
從2011年開始我們致力于在生命科學(xué)領(lǐng)域、生物醫(yī)學(xué)實驗技術(shù)及論文潤色服務(wù)，協(xié)助客戶各類實驗服務(wù)及論文潤色十余年，是客戶您值得信賴的科研合作伙伴!
如果您受時間、試驗條件等限制而無法完成您的課題研究，歡迎您與我們聯(lián)系。
實驗技術(shù)服務(wù)：
